parkinson's syndrome — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1308	Orphenadrine hydrochloride	Mebedrol,Mephenamin	Sodium Channel , NMDAR , Norepinephrine , iGluR , Histamine Receptor
	Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
T1476	Pramipexole	SND 919	Dopamine Receptor
	Pramipexole (SND 919) is a selective dopamine receptor agonist used in the therapy of Parkinson disease. Pramipexole therapy is associated with a low rate of transient serum enzyme elevations during treatment but has not...		Dopamine Receptor
T6618	Orphenadrine Citrate	Flexon,Flexoject,Banflex	AChR , iGluR
	Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.		AChR , iGluR
T6951	Pramipexole dihydrochloride hydrate	Pramipexole 2HCl Monohydrate,Mirapex	Dopamine Receptor
	Pramipexole dihydrochloride hydrate (Mirapex) is the hydrochloride salt of pramipexole, a benzothiazole derivative. As a nonergot dopamine agonist, pramipexole binds to D2 and D3 dopamine receptors in the striatum and su...		Dopamine Receptor
T68026	(Rac)-GSK 372475		Others
	(Rac)-GSK 372475 may be investigated for the treatment of Parkinson's syndrome, depression and obesity.		Others
T22638	CBiPES hydrochloride	CBiPES HCl	GluR
	CBiPES hydrochloride (CBiPES HCl) is a potent orthosteric modulator of the mGlu2 receptor with an EC50 value of 92.8 nM.CBiPES hydrochloride blocks the action of WT and mGlu(3) receptors.CBiPES hydrochloride can be used ...		GluR
T28367L1	BDBM50597431		NMDAR
	BDBM50597431 is an NMDA receptor modulator that may have can be used to study Alzheimer's disease and Parkinson's syndrome.		NMDAR
T34616	Seridopidine	ACR-343,ACR 343,ACR343	Dopamine Receptor
	Seridopidine (ACR343) is a modulator of dopaminergic activity that is used as an oral therapy for schizophrenia, Parkinson's disease, and Tourette's syndrome.		Dopamine Receptor
T29955	AMC-01	AMC01,AMC 01	Antiviral , PERK
	AMC-01 has potential antiviral activity and induces dose- and time-dependent inactivation of eIF2-α via phosphorylation of serine residue 51. AMC-01 can be used to study atherosclerosis and Parkinson's syndrome.		Antiviral , PERK
T6552	Istradefylline	KW-6002	Adenosine Receptor
	Istradefylline (KW-6002)(Ki of 2.2 nM) is a selective adenosine A2A receptor (A2AR) antagonist, which is under development in Phase 3 trails. It has been used in trials studying the treatment and basic science of Drug Ab...		Adenosine Receptor
T6651L	Safinamide	EMD1195686,FCE26743,FCE 26743,EMD-1195686,EMD 1195686,FCE-26743	MAO
	Safinamide (FCE-26743) is a reversible and selective monoamine oxidase B (IC50 0.098μM) inhibitor, reducing the degradation of dopamine, and a glutamate release inhibitor (IC50 8μM). It also inhibits dopamine reuptake. S...		MAO
T27127	DCAT Maleate	DCAT
	DCAT Maleate is an inhibitor of N-methyl transferases (NMT). DCAT Maleate methylate non-methylated pre-neurotoxins to prevent the formation of Parkinson's syndrome neurotoxins.
T77995	NNZ 2591
	NNZ 2591, a synthetic analogue of cyclic glycine-proline (cGP), exhibits oral activity and the ability to cross the blood-brain barrier. This compound demonstrates neuroprotective properties following ischemic brain inju...